Anti Ulcer and Antispasmodic Activity of Udaranoi Nivarana Thiravagam

Abstract

ABSTRACT
Background:
An ulcer is defined as a disruption of the mucosal integrity of the stomach or duodenum, leading to a local defect or excavation due to active inflammation. Ulcers occur within the stomach or duodenum and are often chronic. In Siddha, Peptic ulcer is compared with the disease Kunmam. It mainly occurs due to the imbalance in the pH of the stomach.The drug Udara Noi NivaranaThiravagam is effective in normalising the pH of the stomach and reducing the incidence of Peptic ulcer. Thiraavagam means strong liquid. They are all liquid preparation obtained by a process of destructive distillation of salts and alkalies with or
without any addition of fluids in a peculiar distillation set-up called “Valaiyanthiram”. Thiraavagam and theneer are both analogous to each other in many respects. Both are liquid preparations and are obtained by a common process, namely distillation. Thiraavagam is a product of destructive distillation. The present study aimed to validate the anti-ulcer and antispasmodic properties of Udara Noi Nivarana Thiravagam
Methods:
The drug Udara Noi Nivarana Thiravagam is a herbo-mineral formulation taken from Anuboga vaidya Navaneetham. Which has been indicated for its anti-ulcer and antispasmodic properties. All the ingredients in the drug were properly collected, preserved and authenticated by experts. The Ingredients are purified properly as per the traditional Siddha Literature. The anti-ulcer study is done by the Pyloric ligation method and anti-spasmodic activity on isolated rabbit ileum.
Result:
It was observed that Anti-ulcer and anti-spasmodic studies of UNT showed that it has excellent anti-ulcer activity and mild anti-spasmodic activity.
Conclusions:
It was concluded the drug Udara Noi Nivarana Thiravagam is efficient in healing peptic ulcers and its manifestations.