Antibacterial Activity of Siddha Formulation Vellampattai Kopali Keyalam Against Klebsiella Pneumonia and Streptococcus Pyogenes for Oral Hygeine

Abstract

ABSTRACT
Background:
Poor oral health characterized by inadequate hygiene may result in the formation of extensive dental biofilms (plaque) may promote oral colonization pathogens. Siddha medicine plays a major role in the oral health care system. The Siddha literature “Anuboga vaithiya bhrama ragaseyam” mentioned the “Vellampattai kopali keyalam” for oral hygiene and prevent from periodontal disease. Siddha system of medicine has to be validated through scientific aspect.
Objective:
The aim of the study is to evaluate the anti-microbial activity of Vellampattai kopali keyalamto prevent oral infection
Method:
Vellampattai kopali keyalam is an efficient Siddha formulation used to prevent oral infection. One of the important ingredients is Veppam pattai scientifically known as Azidarchia indica which is found to have antibacterial effect. In the present study, the antibacterial susceptibility test for Vellampattai kopali keyalam done using disc diffusion method on agar. The plate was observed for formation of zone of inhibition around the disc. The diameter of the zone of is directly proportional to the sensitivity of Klbesiella pneumonia and Streptococcus mutans against this formulation. This study revealed the antimicrobial activity
of Siddha formulation “Vellampattai kopali keyalam”.
Result:
The current study was observed from the results of the present investigation that the sample revealed that Vellampattai kopali keyalam convincing anti-microbial activity among all tested organisms. It was observed that the sample reveals significant activity against the pathogen Streptococcus pyogenes (MIC 1000 µg) and Klebsiella pneumonia-KP (MIC 500 µg) maintain the oral hygiene.
Conclusion:
The study therefore supports the siddha formulation to have potent anti-microbial activity and offers profound therapeutic effects against periodontal disease and improve oral hygiene.